2010 Weinstein Cardiovascular Development Conference Keynote presentation

Denis Duboule, PhD

Professor Federal Institute of Technology

Chair of the Department of Zoology and Animal Biology, University of Geneva

Chair for the national center of research ‘Frontiers in Genetics’ and current full professor at the Federal Institute of Technology (EPFL) in Lausanne, Denis Duboule is considered one of the world’s key specialists in developmental biology. His pioneering work on Hox gene clusters, revealing their basic mechanistic functions during developmental processes, launched forth a line of research which remains today one of the most intensively studied systems in biology. »expand

Frank Grosveld, PhD

Professor Erasmus University Rotterdam

Chair of the Department of Cell Biology

Frank Grosveld is Chair of Cell Biology at the Erasmus University Rotterdam, where "Mechanisms of gene regulation and epigenetic phenomena" have been the primary focus of his research. His group carried out pioneering work in many aspects of gene regulation from concluding that DNA methylation inhibits gene expression via an indirect mechanism, to the first description of a locus control region (LCR), visualizing the primary transcription process in the nucleus and most recently the description of 3D interactions in the nucleus. His group has filed a considerable number of patents and has closely collaborated with industrial partners. »expand